Table of Contents

Friday 3 July

13.00 – 13.30 Genome-wide identification of orthologs and phylogenetic gene tree reconstruction Ilan Wapinski (Broad Institute of MIT and Harvard, Cambridge, MA USA)

13.30 – 14.00 Whole Genome Orthology Prediction Among Amniotes Leo Goodstadt (MRC Functional Genetics Unit, University of Oxford, UK)

14.00 – 14.30 Annotating Gene Histories Guy Perriere, (University of Lyon, France)

14.30 – 15.00 Orthologs as the New Homologs – Evolution and Functional Inference William Pearson (William Pearson, USA)

15.00 – 15.30 Phylogeny-Based Prediction of Orthology at Genomic Scales: Challenges and Opportunities Toni Gabaldon (Centre for Genomic Regulation, Spain)

16.00 – 16.20 Classifying of orthology relation and inferring protein interaction from correlations of evolutionary distances Teresa Przytck ( NIH, USA)

16.20 – 16.50 Orthology, Paralogy and Beyond: Annotating Gene Function using Evolutionary Trees Paul Thomas (SRI International, USA)

16.50 – 17.20 Albert Vilella (EBI, UK)

17.20 – 17.50 Orthology Prediction in the Twilight Zone Martijn Huynen (Radboud University Nijmegen Medical Centre, Netherlands)

Sat 4 July

09.00 – 09.20 Using Synteny to Sort Out Reciprocal Gene Loss and Rapid Ortholog Divergence in Yeast Species Ken Wolfe (Smurfit Institute of Genetics, Ireland)

09.20 – 09.40 Yeast researches need well-defined orthology dataset Mike Cherry (Stanford University USA)

09.40 – 10.10 Erik Sonnhammer (Stockholm University, Sweden)

10.10 – 10.40 Efficient Bayesian Reconstruction and Reconciliation of Thousands of Gene Family Phylogenies Across Multiple Complete Genomes Matt Rasmussen/Manolis Kellis (MIT, USA)

11.10 – 11.40 The Gene Ontology's Reference Genome Project: a Unified Framework for Functional Annotation across Species Pascale Gaudet (Northwestern University, USA)

11.40 – 12.10 PAINT: The GO Workbench for Protein Family Annotation Suzanna Lewis, Lawrence Berkeley National Laboratory, USA

12.10 – 12.40 Orthologs, Paralogs, and Functional Annotations Using The Gene Ontology Judy Blake (The Jackson Lab, USA)

12.40 – 13.10 ProGMap: an integrated annotation resource for protein orthology Jack Leunissen/Sandor Pongor (Wageningen University, Netherlands)

13.40 – 14.00 HCOP: A one stop orthology shop Michael Lush (HGNC, UK)

14.00 – 14.20 MBGD and RECOG: integrated platform for comparative genomics based on large-scale ortholog grouping Ikuo Uchiyama (National Institute for Basic Biology, Japan)

14.20 – 14.40 OMA – Orthology Inference Among 830 Complete Genomes Christophe Dessimoz (ETH Zurich, Switzerland)

16.00 – 16.30 Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods Adrian Altenhoff (ETH Zurich, Switzerland)

16.30 – 16.50 How Evolutionary Analyses Impacts on New Medicines Julie Huxley-Jones, (GlaxoSmithKline Pharmaceuticals, UK)

16.50 – 17.10 Ohnologs gone missing: The problem of orthology assignmente after whole genome duplication John Postlethwait, (University of Oregon, USA)

17.10 – 17.30 eggNOG v2.0: evolutionary genealogy of genes Non-supervised Orthologous Groups Jean Muller, (EMBL, Germany)

17.30 – 18.00 OrthoMCL: Robust Automated Multi-Species Ortholog Identification David Roos (University of Pennsylvania, USA)

Sun 5 July

09.00 – 09.30 Sequencing, Sequencing and Sequencing Jun Wang (Beijing Genomics Institute-Shenzhen, China) Incorporating Species Phylogeny in the Reconstruction of Gene Trees Heng Li (Wellcome Trust Sanger Institute UK)

09.30 – 09.50 Conservation and Consequences of Alternative Splicing in Human and Mouse Jennifer Harrow, (Wellcome Trust Sanger Institute, UK)

09.50 – 10.20 UniProtKB: Both a User of and a Hub for Phylogenomic Information Brigitte Boeckmann (Swiss Institute of Bioinformatics, Switzerland)

10.50 – 11.10 Identifying the Orthologs of Pig Genes Alan Archibald (University of Edinburgh, UK)