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List of orthology databases

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Database Description / Scientific focus applications (Max. 2 sentences) Last updated Update frequency QFO Reference Proteomes Taxonomic range covered Number of organisms Web service available OrthoXML available
DIOPT Integrative ortholog prediction tool of 10 algorithms 2016 partially major model organisms 9 yes no
Ensembl Compara Evolutionary relationships among Ensembl species genes; Projection of gene names and GO annotations 2016 4-5x / year no all domains of life through 6 divisions (sets of species) 66 chordates and 240 others yes yes
InParanoid Database of 2-species ortholog groups with inparalogs; inparalogs and seed orthologs are assigned a confidence score 2014 yes all domains of life, mostly eukaryotic 273 no yes
OMA Phylogenetic reconstruction, function prediction and ancestral genome content through different types of orthologous groups 2016 2x / year partially all domains of life >1800 yes yes
PANTHER Evolutionary relationships among model organism genes; Inference of gene function using GO terms 2016 yearly yes all domains of life 104 yes no
PLAZA Plant comparative genomics database, focusing on dicots, monocots and green algae. More info about data types here 2014 no Viridiplantae Dicots 3.0 31, Monocots 3.0 16 no no
TreeFam Catalogue of gene families; Phylogenetic reconstruction 2012 Next update in 2015 no metazoans + model eukaryotes 109 no no
Other databases: