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orthology_databases [2017/11/30 15:44]
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orthology_databases [2023/11/24 12:57] (current)
Diego Fuentes Updated Metaphors
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 | [[http://​www.greenphyl.org/​|GreenPhylDB]] | Database for comparative and functional genomics in plants. gene family clustering, manual curation and phylogenomic inference of orthologs | 2014 | variable | no |  Viridiplantae ​ | 37  | yes | no | | [[http://​www.greenphyl.org/​|GreenPhylDB]] | Database for comparative and functional genomics in plants. gene family clustering, manual curation and phylogenomic inference of orthologs | 2014 | variable | no |  Viridiplantae ​ | 37  | yes | no |
 | [[http://​hieranoidb.sbc.su.se/​|HieranoiDB]] | Database of ortholog trees inferred by Hieranoid; speciation and duplication nodes are marked; inparalogs are assigned a confidence score | 2016 |     | yes | all domains of life  | 66 | no | yes | | [[http://​hieranoidb.sbc.su.se/​|HieranoiDB]] | Database of ortholog trees inferred by Hieranoid; speciation and duplication nodes are marked; inparalogs are assigned a confidence score | 2016 |     | yes | all domains of life  | 66 | no | yes |
-| [[http://inparanoid.sbc.su.se/​|InParanoid]] | Database of 2-species ortholog groups with inparalogs; inparalogs and seed orthologs are assigned a confidence score | 2014 |     | yes | all domains of life, mostly eukaryotic ​ | [[http://inparanoid.sbc.su.se/cgi-bin/summary.cgi|273]]  | no | yes | +| [[http://inparanoidb.sbc.su.se/​|InParanoiDB]] | Database of 2-species ​full-length protein and domain ​ortholog groups with inparalogs; inparalogs and seed orthologs are assigned a confidence score | 2023 |     | yes | all domains of life  | [[https://inparanoidb9.sbc.su.se/statistics/|640]]  | no | yes | 
-| [[http://betaorthology.phylomedb.org/​|metaPhOrs]] | Phylogeny-based orthologs and paralogs computed using a consistency-based algorithms and phylogenetic trees available in 12 public repositories | 2015 | | yes | all domains of life | 2,714 | yes | no | +| [[http://orthology.phylomedb.org/​|metaPhOrs]] | Phylogeny-based orthologs and paralogs computed using a consistency-based algorithms and phylogenetic trees available in 12 public repositories | 2021 | | yes | all domains of life | 6,384 | yes | no | 
-| [[http://​omabrowser.org/​|OMA]] | [[http://​omabrowser.org/​oma/​about|Phylogenetic reconstruction,​ function prediction and ancestral genome content through different types of orthologous groups]] | 2017 | 2x / year  | partially | all domains of life | >2000 | [[http://​omabrowser.org/​oma/APISOAP|yes]] ​ | yes |+| [[http://​omabrowser.org/​|OMA]] | [[http://​omabrowser.org/​oma/​about|Phylogenetic reconstruction,​ function prediction and ancestral genome content through different types of orthologous groups]] | [[https://​omabrowser.org/​static/​image/​history.png|2023]] ​| 2x / year  | partially | all domains of life | >2500 | [[http://​omabrowser.org/​api/docs|yes]] ​ | yes |
 | [[http://​orthodb.org/​|OrthoDB]] | Comparative genomics, gene function inference, phylogenomics | [[http://​www.ncbi.nlm.nih.gov/​pubmed?​cmd=Search&​term=27899580|2016]] | yearly ​ | no | all domains of life and viruses | >4000 Prok., 588 Euk., & >3000 vir. | [[http://​www.orthodb.org/?​page=api|yes]] ​ | no | | [[http://​orthodb.org/​|OrthoDB]] | Comparative genomics, gene function inference, phylogenomics | [[http://​www.ncbi.nlm.nih.gov/​pubmed?​cmd=Search&​term=27899580|2016]] | yearly ​ | no | all domains of life and viruses | >4000 Prok., 588 Euk., & >3000 vir. | [[http://​www.orthodb.org/?​page=api|yes]] ​ | no |
 | [[http://​www.lbgi.fr/​orthoinspector/​|OrthoInspector]] | Databases of pairwise orthology and inparalogy relationships | 2015 | | yes | all domains of life | 259 Eukaryotes, 1688 Prokaryotes | yes |yes | | [[http://​www.lbgi.fr/​orthoinspector/​|OrthoInspector]] | Databases of pairwise orthology and inparalogy relationships | 2015 | | yes | all domains of life | 259 Eukaryotes, 1688 Prokaryotes | yes |yes |
 | [[http://​www.pathogenomics.sfu.ca/​ortholugedb/​|OrtholugeDB]] | Ortholog predictions for completely sequenced bacterial and archaeal genomes, with additional assessment using Ortholuge to improve specificity | 2016 | 1x / year | no | bacteria and archaea | >2000 | yes | yes | | [[http://​www.pathogenomics.sfu.ca/​ortholugedb/​|OrtholugeDB]] | Ortholog predictions for completely sequenced bacterial and archaeal genomes, with additional assessment using Ortholuge to improve specificity | 2016 | 1x / year | no | bacteria and archaea | >2000 | yes | yes |
-| [[http://​www.pantherdb.org/​|PANTHER]] ​  | Evolutionary relationships among model organism genes; Inference of gene function using GO terms    | 2016 | yearly | yes | all domains of life | [[http://​pantherdb.org/​panther/​summaryStats.jsp|104]]  | [[http://​pantherdb.org/​help/PANTHERhelp.jsp#V.A.|yes]] ​ | no +| [[http://​www.pantherdb.org/​|PANTHER]] ​  | Evolutionary relationships among model organism genes; Inference of gene function using GO terms    | 2023 | yearly | yes | all domains of life | [[http://​pantherdb.org/​panther/​summaryStats.jsp|143]]  | [[http://​pantherdb.org/​services/index.jsp|yes]] ​ | yes 
-| [[http://​phylomedb.org/​|PhylomeDB]] | Genome-wide collection of gene evolutionary histories, and phylogeny-based orthology and paralogy prediction | 2016 | | yes  |  all domains of life  | >1000 | yes | yes |+| [[http://​phylomedb.org/​|PhylomeDB]] | Genome-wide collection of gene evolutionary histories, and phylogeny-based orthology and paralogy prediction | 2023 | | yes  |  all domains of life  | >1000 | yes | yes |
 | [[http://​bioinformatics.psb.ugent.be/​plaza/​|PLAZA]] | Plant comparative genomics database, focusing on dicots, monocots and green algae. More info about data types [[http://​bioinformatics.psb.ugent.be/​knowledge/​wiki-plaza/​data_content|here]]| 2014 | | no | Viridiplantae ​ | Dicots 3.0 [[http://​bioinformatics.psb.ugent.be/​plaza/​versions/​plaza_v3_dicots/​|31]],​ Monocots 3.0 [[http://​bioinformatics.psb.ugent.be/​plaza/​versions/​plaza_v3_monocots/​|16]] ​ | no | no | | [[http://​bioinformatics.psb.ugent.be/​plaza/​|PLAZA]] | Plant comparative genomics database, focusing on dicots, monocots and green algae. More info about data types [[http://​bioinformatics.psb.ugent.be/​knowledge/​wiki-plaza/​data_content|here]]| 2014 | | no | Viridiplantae ​ | Dicots 3.0 [[http://​bioinformatics.psb.ugent.be/​plaza/​versions/​plaza_v3_dicots/​|31]],​ Monocots 3.0 [[http://​bioinformatics.psb.ugent.be/​plaza/​versions/​plaza_v3_monocots/​|16]] ​ | no | no |
 | [[http://​www.treefam.org/​|TreeFam]] ​   | [[http://​www.treefam.org/​browse|Catalogue of gene families]]; [[http://​www.treefam.org/​help#​tabview=tab1|Phylogenetic reconstruction]] | 2012 | Next update in 2015 | no |  metazoans + model eukaryotes ​ | [[http://​www.treefam.org/​browse#​tabview=tab1|109]] ​  | no | no | | [[http://​www.treefam.org/​|TreeFam]] ​   | [[http://​www.treefam.org/​browse|Catalogue of gene families]]; [[http://​www.treefam.org/​help#​tabview=tab1|Phylogenetic reconstruction]] | 2012 | Next update in 2015 | no |  metazoans + model eukaryotes ​ | [[http://​www.treefam.org/​browse#​tabview=tab1|109]] ​  | no | no |